EFFECTIVENESS TEST OF SEMBUNG RAMBAT LEAF EXTRACT (MIKANIA MICRANTHA KUNTH) AND ALOE VERA GEL ON HEAD LICE (PEDICULUS HUMANUS CAPITIS) MORTALITY

Abstrak

ABSTRACT

Presence of potential side effects and resistance as well as ineffectiveness of pyrethrin and pyrethroid-based pediculicides so that a new therapy is needed in managing head lice (Pediculus humanus capitis). The development of sembung rambat (Mikania micrantha Kunth) and aloe vera gel contains secondary metabolites such as flavonoids which have the potential to eradicate head lice. This research aims determine the effectiveness of a mixture of Mikania micrantha Kunth leaf extract and Aloe vera gel on the mortality of head lice. This is a true experimental design study with a post test only control group, consist of a positive control using 1% permethrin and a negative control using aquadest and treatment groups using a mixture of Mikania micrantha Kunth leaf and Aloe vera gel with a ratio of 30:70, 50:50, 70 :30. The treatment group had a mortality percentage from highest to lowest at 240 minutes P2 of 63.33%, P3 of 60%, P1 of 43.33 %. As for the results of the one-way ANOVA test, the difference in the average percentage of head lice mortality in the test group was p <0.05. A mixture of Mikania micrantha Kunth leaves and Aloe vera gel is effective in causing head lice mortality.

ABSTRAK

Adanya potensi efek samping dan resistensi serta ketidakefektifan piretrin dan pedikulisida berbasis piretroid sehingga diperlukan terapi baru dalam penanganan kutu rambut (Pediculus humanus capitis). Perkembangan sembung rambat (Mikania micrantha Kunth) dan gel lidah buaya mengandung metabolit sekunder seperti flavonoid yang berpotensi membasmi kutu rambut. Penelitian ini bertujuan untuk mengetahui efektivitas campuran ekstrak daun Mikania micrantha Kunth dan gel lidah buaya terhadap mortalitas kutu rambut. Ini adalah penelitian desain eksperimen sejati dengan post test only kelompok kontrol, terdiri dari kontrol positif menggunakan permetrin 1% dan kontrol negatif menggunakan aquadest dan kelompok perlakuan menggunakan campuran Mikania micrantha daun Kunth dan gel lidah buaya dengan perbandingan 30:70, 50:50, 70:30. Kelompok perlakuan memiliki persentase mortalitas dari tertinggi ke terendah pada 240 menit P2 sebesar 63,33%, P3 sebesar 60%, P1 sebesar 43,33%. Sedangkan untuk hasil uji one-way ANOVA, perbedaan rata-rata persentase kematian kutu rambut pada kelompok uji adae Vera Gel, Mikania Micrantha Kunth Leaf, Mortality, Pediculocide, Head Lice.lah p <0,05. Campuran daun Mikania micrantha Kunth dan gel lidah buaya efektif dalam menyebabkan kematian kutu kepala.